Can I take Sleep every night? Trish February 11, 2020 17:26 Updated Follow Yes. Sleep is safe to take every night. Sleep's natural ingredients should not lead to any kind of dependence. Related articles Will Sleep work the first time I use it? Are there any side effects to Sleep? Will I feel different after taking Daily Cleanse? Will taking Sleep make me groggy? Can I take In The Mood with my birth control pill? Comments 0 comments Please sign in to leave a comment.